Angaelos was born in Cairo, Egypt and emigrated with his family to Australia, where he spent his childhood years. He obtained a Bachelor of Arts, majoring in political science, philosophy and sociology, and went on to postgraduate studies in law whilst working in the same field. In 1990, Angaelos returned to Egypt to join the Monastery of Saint Bishoy in Wadi-El-Natroun, where he was subsequently consecrated a monk by Pope Shenouda III. He served as Papal secretary until 1995, and was then delegated by the Pope to serve as a parish priest in the United Kingdom. He was consecrated in 1999 as a General Bishop (a rank between auxiliary bishop and chorbishop) in the United Kingdom of the Coptic Orthodox Church. He was then enthroned as the first Coptic Orthodox Archbishop of London (ecclesial title given by Pope Tawadros II) on 18 November 2017